Bukayo Saka has left the England camp after testing positive for COVID-19.
Saka trained with his international teammates on Tuesday but had been isolated from the rest of the squad since Wednesday.
The Arsenal youngster has now returned home.
He tweeted: “I am gutted to withdraw from @England camp but I have tested positive for COVID-19 and I will be isolating until I am negative, The Trumpet gathered.
“I’ll be supporting the boys from home this weekend and I can’t wait to be back doing what I love soon.”
England manager, Gareth Southgate, who has seen a few withdrawals from his initial 25-man squad, will not call up a replacement for Saka.
Saka is the sixth player to withdraw from the squad after Trent Alexander-Arnold, Reece James, Tammy Abraham and Aaron Ramsdale.
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Gunner boss, Mikel Arteta, will be hoping to have the 20-year-old fit and available for their difficult trip to Crystal Palace after the international break.
Saka scored the only goal as Arsenal beat Aston Villa 1-0, before joining up with the Three Lions.